"By cleverly combining new techniques for analyzing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia," predicts Professor John ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

Miami University’s Center for Bioinformatics and Functional Genomics (CBFG) has become one of the first institutions in the region to acquire the PacBio VEGA Benchtop System — a cutting-edge DNA ...

DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...

PacBio has announced plans to enhance its methylation detection capabilities in HiFi sequencing by licensing advanced methods from Professor Dennis Lo and his team at The Chinese University of Hong ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...