For years, two siblings with the distinctive facial features of Treacher Collins syndrome had no genetic explanation for ...
Gene amplifications and deletions frequently have pathogenetic roles in cancer. 30,000 radiation-hybrid mapped cDNAs provide a genomic resource to map these lesions with high resolution. We developed ...
We have generated transgenic mice carrying targeted deletions of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) gene. These animals offer the unique opportunity to gain insights into ...
The ventral tegmental area (VTA) is a key site for opioid actions, and emerging evidence suggests that pain states and opioid experience both induce transcriptional, molecular, and circuit adaptations ...
A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand ...