(+)-Pleuromutilin is a structurally intricate natural antibiotic featuring a densely functionalized 5/6/8 tricyclic core and eight contiguous stereocenters. Here, the authors report a bioinspired ...
A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...
∥ Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu 808-0196, Japan ⊥ New Energy Science & Engineering Programme, ...
Key Laboratory for Anisotropy and Texture of Materials, Ministry of Education, School of Materials Science and Engineering, Northeastern University, 3-11 Wenhua Road, Shenyang 110819, P. R. China ...