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AI tools advance genomic analysis from crops to clinical care

Recent advances in artificial intelligence are reshaping genomics, with new tools enabling faster, more accurate genome annotation, variant detection, and functional prediction across agriculture and ...
Government Executive

NIST is giving fingerprint examiners better tools for a messy job

A newly annotated fingerprint dataset combined with open-source software could help forensic examiners work more consistently ...
eLife

The long-range gene regulatory landscape of cerebellar granule neuron progenitors

Neuronal specification, expansion and differentiation are tightly regulated by the concerted actions of transcription and chromatin modifying factors that are recruited to regulatory elements in the ...
News-Medical.Net

A closer look at plant metabolomics with timsTOF Ultra

With the timsTOF Ultra, researchers can now dive into single-cell metabolomics in plants, offering a clearer, more detailed look at how alkaloids are made and where they’re coming from.
gut.bmj

Stage-dependent gut microbiome and functional signatures across the liver disease spectrum: an integrative multicohort study

Background The gut-liver axis plays a critical role in liver disease progression; however, how gut microbial ecology and function vary across disease stages remains unclear. Objective To define ...
IEEE

scGraphDap: Integrating Functional State Pseudo-labels and Graph Structure Learning for Robust Cell Type Annotation in Tumor Microenvironments

Abstract: The tumor microenvironment is a dynamic eco system where cellular interactions drive cancer progression. However, inferring cell-cell communication from non-spatial scRNA-seq data remains ...
marktechpost

A Coding Guide to Build a Complete Single Cell RNA Sequencing Analysis Pipeline Using Scanpy for Clustering Visualization and Cell Type Annotation

In this tutorial, we build a complete pipeline for single-cell RNA sequencing analysis using Scanpy. We start by installing the required libraries and loading the PBMC 3k dataset, then perform quality ...
GitHub

A Nextflow Pipeline for Gene Prediction and Functional Annotation

GeneForge is a flexible Nextflow pipeline for gene prediction and optional functional annotation of eukaryotic genomes. It integrates BRAKER3 and FunAnnotate for gene prediction, compares their ...
C&EN

Metabolite Identification Data in Drug Discovery, Part 2: Site-of-Metabolism Annotation, Analysis, and Exploration for Machine Learning

Department of Pharmaceutical Sciences, Division of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria Medicinal Chemistry, Research ...
PNAS

Scalable and accurate rare-variant association tests for whole genome sequencing time-to-event analysis in large biobanks

Rare variants (RV) identified through whole genome sequencing hold great promise for elucidating the genetic basis of disease onset, but existing methods for RV association testing are not well suited ...
GitHub

cdg1921/dify_annotation_and_analysis

本项目为开源项目DIFY源码注释与解析（源码链接），以帮助更多的同学学习和理解DIFY源码，以便更快地进行二次开发和优化 ...